After suffering a brain injury that wipes out the past eight years of her memory, Dr. Amy Larsen finds herself in a world she no longer recognizes. She must depend on her 17-year-old daughter, who she still envisions as a 9-year-old, and a few loyal friends. As she grapples with the challenge of resuming her medical career, she faces the daunting task of doing so without the benefit of nearly ten years of lost expertise and experience.