Brothers & Sisters is a U.S. television drama that revolves around the Walker family and their experiences in Pasadena, California. The show debuted on ABC on September 24, 2006, and concluded on May 8, 2011. Throughout its entire run, it was broadcast in a Sunday night slot following Desperate Housewives.

The series featured a lineup of acclaimed actors, such as Sally Field, Rachel Griffiths, Calista Flockhart, Rob Lowe, and Patricia Wettig. Sally Field earned both a Primetime Emmy Award and a Screen Actors Guild Award for her role in the series. Rachel Griffiths also received nominations for two Primetime Emmy Awards and two Golden Globe Awards for her performance.

In May 2011, Brothers & Sisters wrapped up its fifth and final season on ABC. On May 13, 2011, ABC announced the show’s cancellation.