Detective Catherine Chandler is a sharp and pragmatic investigator specializing in homicide cases. As a teenager, she witnessed her mother’s murder by two gunmen and was rescued by an unknown entity. Years later, while probing a murder case, Catherine stumbles upon evidence that leads her to Vincent Keller, a man believed to have died in 2002. She discovers that Vincent is, in fact, alive and was the one who saved her life years ago. Due to enigmatic circumstances that compel him to live on the fringes of society, Vincent has been in seclusion for the past decade to protect his secret: when he becomes angry, he transforms into a formidable beast, losing control over his immense strength and enhanced senses.