In an unexpected turn of events, PCP contaminates Frankfurt’s water system, causing the zoo animals to go berserk. One night, a security failure at the zoo allows these frenzied creatures to escape and unleash chaos across the city, indulging in a spree of destruction and bloodshed. The task of restoring order falls to Lorraine De Selle, a frequent star of Italian B-movies, and John Aldrich, a zookeeper who bears a striking resemblance to an irritable Super Mario.