Caleb and his six college buddies are preparing for an unforgettable Halloween bash when they inadvertently release a hidden biological serum in the quaint rural town of Lakeshear. This serum turns those exposed into frenzied, mindless killers. Unaware, Caleb becomes infected and must rely on his friends to help him discover a cure for this lethal contagion before time runs out. Who is behind the creation of this serum? And how far will these seven friends have to go to halt its deadly spread?